Caladryl Calamine Plus Anti-Itch Topical Analgesic/Skin Protectant is a topical analgesic and skin protectant lotion that provides drying action and itch relief. Dries the oozing and weeping of poison ivy, poison oak and poison sumac. Temporarily relieves pain and itching associated with rashes due to poison ivy, poison oak, or poison sumac insect bites minor skin irritation minor cuts.