EASY TO APPLY - Dr. John Lee recommended using 20 - 40 mg. of bio-identical progesterone cream twice daily. Gently massage 1/8 to 1/4 teaspoon into a thin-skinned area of the body such as the neck, face, breastbone, forearms, etc. You may alternate application site. Use twice daily—morning and night. (Add additional use directions?). FOR MATURE WOMEN - Especially helpful for women with excess estrogen or "estrogen dominance". It provides a calming effect, supports the natural hormonal rhythms of your body, and aids in reducing hot flashes. BALANCING CREAM - Formulated WITHOUT phytoestrogens, this healthy balancing cream is toxin, GMO, gluten and fragrance free. As per Dr. John Lee's strict criteria, each 1/4 teaspoon of Feminine Balance Therapy provides approximately 20 mg. of bio-identical USP progesterone to help alleviate the unwanted symptoms of hormonal changes. MADE IN THE USA - Made in the USA in a GMP certified facility, this product combines select organic herbs and other healthful ingredients to safely and effectively bring excellent results to adult women of all ages. RESTORATIVE FORMULA - Feminine Balance Therapy Bio-Identical Progesterone Cream from Organic Excellence helps restore healthy progesterone levels to support natural hormonal balance. It is especially helpful for eg the symptoms associated with estrogen dominance during perimenopause. Women with PMS, PCOS, and fertility issues may benefit from this toxin-free, all natural product.