Also we incubate our Nano HP with the silver. See studies on silver infused Nano HP.336 silver according to safe groundwater standards- Collodial silver does have toxicity guidelines, but its a great tool if used correctly. This product can not be intended to cure treat or prevent any disease, as these ingredients have not been evaluated by the FDA for such claims. This product is intended purely as a cosmetic. Please research for yourself the international studies that are available on the effectiveness and safety of theobromine and nano hydroxyapatite. High percentage of xylitol ( 25 ) with no glycerin or compromised fillers, preservatives, or sweeteners- children love the chocolate mint and vanilla flavor! All food grade and vegan friendly- Quality Reputable Brand: Crafted all in the USA by a trusted small family owned cosmetics company committed to alternative oral care products. We dont use synthetic polymer (plastic based ) hydroxyapatite gels or chemically induced suspensions. We apply the most cutting edge approach to incubating our hydroxyapatite. Naturally structured hydrogels create high solubility scaffolding (natural polysaccharide based) for perfect distribution of the high porosity nano HP. Therefore we don't need a high percentage and our paste is more affordable. For example compare our prices to Bliss Energetics Tooth Powder. It is not just about concentration with Nano HP, or even bio availability, but it is also about solubilty. Nano HP is insoluble even at 30 nm it still settles, and then tends to reaggregate into bigger crystals and different structures. Therfore every other company I know of uses Nano HP treated with a chemical or buffered by polymer (plastic) to create the suspension gel. Even fluinova uses potassium chloride, which in their case causes exposed negative ions on the crystals which then repluse from one another electrostaticaly. However the surface of the tooth is naturally negatively charged, so that Nano HP needs an extra calcium ion from somehwere in order to bind. Instead of ultra high Nano HP our paste features 10,000 mg per liter of theobromine. Theobromine is another highly praised and studied remineralization aide. It works as a catalyst alongside the Nano HP calcium and phosphate ions. Also, we are the only producer I know offering bioinductive carbonated Nano HP. All producers I know of use stoichiometric hydroxyapatite which naturally is not as bioavailable. Carbonated Nano HP has been prepared in a way that removes calcium ions from the surface and replaces them with carbonate so that the floating Nano HP becomes attracted to exisiting calcium rich dentin. This is how bone attracts. Essentially the carbonated crystals are more reactive. Our Nano hydroxyapatite has a particle size of 60nm and an abstract ration of 2.2. Only rod shaped morphology has been established as safe after EU consumer safety performed an 8 year intensive study on hydroxyapatite with a team of 11 toxicologists. Up to 30 nano HA is recognized as safe, however more than 10 percent is indicated to have little added benefit. In fact too much can clog the enamel pores and prevent blanced mineral uptake neccesary for remineralization, or it can aggregate and scratch enamel! More is not better. Plus not all types of Nano HP have the same effectiveness. See Below!. Enamel remineralization support that encourages restoration of natural tooth color. Enjoy less sensitivity to heat, cold, and acids. Compare our everyday clay paste to Uncle Harry's Tooth Powder: Our blend offers a hydrated paste with theobromine and nano hydroxyapatite!.