O’Keeffe’s Working Hands Night Treatment is a calming yet intense, restorative hand cream that is to relieve extremely dry, cracked hands while you sleep. For best results apply after hand washing, after bathing, and at bedtime, as these are the most effective times for moisturizing extremely dry skin. Makes a difference you will feel within days. Creates a protective layer on the skin’s surface that instantly boosts moisture levels and helps prevent further moisture loss. O’Keeffe’s Working Hands Hand Cream is a concentrated hand cream that heals, relieves and repairs extremely dry, cracked hands.