Adults and children 2 years of age and older: Apply a thin layer to the affected area. Do not reinsert dental work until irritation/pain is relieved. Rinse out well before reinserting. use up to 4 times daily or as directed by a physician or healthcare provider. This preparation is intended for use in cases of denture pain, only as a temporary expedient until a physician can be consulted. Orajel Denture Pain Gel will stay in place for extended duration of relief.